Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diagnosis using next-generation...

Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diagnosis using next-generation DNA sequencing - Manson-Bahr et al. - Journal of Clinical Pathology

This is a methodology paper from us that describes a new technique for obtaining DNA from prostate cancer biopsy tissue stored in FFPE.  We go on to show that the quantity and quality of DNA is good enough for targeted next-generation sequencing to be performed reliably.  This is important because it shows that targeted sequencing can be used as a test in the clinic without changes to the pathology processing that is currently performed in hospitals.
http://jcp.bmj.com/content/early/2015/01/13/jclinpath-2014-202754.abstract

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